Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.88 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.88 |
| ▸ | IDO1 | P14902 | 2/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.88 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.88 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylhydrazine SCHEMBL27346193 | 0.97 | TDP1 (0.82) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| Phenylhydrazine SCHEMBL9742536 | 0.94 | TDP1 (0.88) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| Phenylhydrazine SCHEMBL7099 | 0.94 | — | — | |
| Phenylhydrazine SCHEMBL28169534 | 0.94 | TDP1 (1.00) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| SCHEMBL20005911 | 0.94 | TDP1 (1.00) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| Phenylhydrazine SCHEMBL28012655 | 0.91 | TDP1 (0.82) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| Phenylhydrazine SCHEMBL28210238 | 0.91 | TDP1 (0.82) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| Phenylhydrazine SCHEMBL16763414 | 0.91 | TDP1 (0.82) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| Phenylhydrazine SCHEMBL10936131 | 0.90 | — | — | |
| Phenylhydrazine SCHEMBL8809529 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117224541-A | Treatment of obesity | 北京强新生物科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-112955143-B | Treatment of non-alcoholic fatty liver disease | 北京强新生物科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-112996507-B | Treatment of obesity | 北京强新生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |