O-Xylene

O-Xylene

SCHEMBL29066360

Cc1cc(C)c(-c2ncc[nH]2)c(C)c1.Cc1ccccc1C

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 2/20 0.49
MTOR P42345 1/20 0.47
ADK P55263 1/20 0.47
ADRA2A P08913 3/20 0.41
TAAR1 Q96RJ0 2/20 0.40
BRD4 O60885 1/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CSNK1A1 P48729 1/20 0.37
TYRO3 Q06418 1/20 0.37
DYRK1B Q9Y463 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
SMPD3 Q9NY59 1/20 0.35
ADRA2C P18825 2/20 0.35
ADRA1D P25100 2/20 0.35
ADRA1A P35348 2/20 0.35
ADRA1B P35368 2/20 0.35
TSHR P16473 1/20 0.34
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284115 0.91 NISCH (0.52) NISCHMTORADKADRA2ATAAR1
Bromide SCHEMBL28735524 0.89 NISCH (0.50) NISCHMTORADKADRA2ATAAR1
Hydrochloric Acid SCHEMBL28055177 0.89 NISCH (0.50) NISCHMTORADKADRA2ATAAR1
SCHEMBL28021715 0.86 NISCH (0.47) NISCHMTORADKADRA2ATAAR1
SCHEMBL29265355 0.86 NISCH (0.47) NISCHMTORADKADRA2ATAAR1
SCHEMBL6001368 0.83 NISCH (0.52) NISCHMTORADKADRA2ATAAR1
Hydrochloric Acid SCHEMBL29265356 0.82 NISCH (0.50) NISCHMTORADKADRA2ATAAR1
SCHEMBL22431423 0.79 NISCH (0.44) NISCHMTORADKADRA2ATAAR1
SCHEMBL28766417 0.79 NISCH (0.47) NISCHMTORADKADRA2ATAAR1
SCHEMBL674011 0.74 NISCH (0.53) NISCHMTORADKADRA2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116539654-A Para-hydrogen hyperpolarization method for realizing high-sensitivity NMR detection of alcohol compounds 厦门大学 2023-08-04 CN disclosed