Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396747 | 0.87 | ABL1 (0.65) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL6942730 | 0.86 | GAA (0.69) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL12955058 | 0.86 | EPHX2 (0.66) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL13671323 | 0.86 | ABL1 (0.64) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL24756629 | 0.85 | EPHX2 (0.48) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL29979667 | 0.84 | NAMPT (0.71) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL12781644 | 0.84 | EPHX2 (0.52) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL13963821 | 0.84 | EPHX2 (0.52) | EPHX2ABL1RIN1KMT2AMEN1 | |
| SCHEMBL25567301 | 0.82 | NAMPT (0.69) | ABL1RIN1KMT2AALDH1A1MAPT | |
| SCHEMBL1374093 | 0.81 | MEN1 (0.68) | ABL1RIN1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185451-B | Memantine urea derivative, and preparation method and application thereof | 沈阳药科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-113185451-A | Memantine urea derivative and preparation method and application thereof | 沈阳药科大学 | 2021-07-30 | — | — | CN | disclosed |