Butanone

Butanone

SCHEMBL29067358

CCC(C)=O.O=C1CCCCCCCCO1

nearest known ligand 0.61

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.61
CA9 Q16790 1/20 0.61
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
PGR P06401 2/20 0.36
FKBP4 Q02790 3/20 0.33
FKBP1A P62942 1/20 0.31
ATM Q13315 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butanone SCHEMBL28283980 1.00 CA1 (0.61) CA1CA9ALDH1A1TDP1LMNA
Butanone SCHEMBL28252360 1.00 CA1 (0.61) CA1CA9ALDH1A1TDP1LMNA
Butyrolactone SCHEMBL2821176 0.92 CA1 (0.54) CA1CA9ALDH1A1TDP1LMNA
Propionic Acid SCHEMBL28374077 0.90 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Acetone SCHEMBL27767208 0.88 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Alcohol SCHEMBL28308931 0.86 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
Alcohol SCHEMBL1274277 0.86 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
Acetic Acid SCHEMBL27560595 0.86 CA1 (0.70) CA1CA9ALDH1A1LMNATP53
Propane SCHEMBL28919185 0.86 CA1 (0.76) CA1CA9ALDH1A1LMNATP53
SCHEMBL27867713 0.85 CA1 (0.61) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660397-A Quality detection method of musk or musk extract for treating acute ischemic stroke 成都中医药大学 2023-08-29 CN claimed
CN-116660397-A Quality detection method of musk or musk extract for treating acute ischemic stroke 成都中医药大学 2023-08-29 CN disclosed
CN-116660397-A Quality detection method of musk or musk extract for treating acute ischemic stroke 成都中医药大学 2023-08-29 CN disclosed