SCHEMBL29067448

SCHEMBL29067448

CCCCNC1CCCc2cccnc21

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
CXCR4 P61073 10/20 0.45
CYP2D6 P10635 5/20 0.40
CYP3A4 P08684 2/20 0.40
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
HTT P42858 1/20 0.39
ADORA2A P29274 1/20 0.39
GRIN1 Q05586 1/20 0.38
GRIN2B Q13224 1/20 0.38
OPRL1 P41146 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30486101 1.00 HDAC1 (0.52) HDAC1HDAC6CXCR4CYP2D6CYP3A4
SCHEMBL14275061 0.96 HDAC1 (0.51) HDAC1HDAC6CXCR4CYP2D6CYP3A4
SCHEMBL4123198 0.92 HDAC1 (0.54) HDAC1HDAC6CXCR4CYP2D6HTT
SCHEMBL4889228 0.92 HDAC1 (0.54) HDAC1HDAC6CXCR4CYP2D6HTT
SCHEMBL3736077 0.92 HDAC1 (0.54) HDAC1HDAC6CXCR4CYP2D6HTT
SCHEMBL3996453 0.88 HDAC1 (0.56) HDAC1HDAC6CXCR4CYP2D6CYP3A4
SCHEMBL30096620 0.86 HDAC1 (0.55) HDAC1HDAC6CXCR4CYP2D6CYP3A4
SCHEMBL4885421 0.86 HDAC1 (0.56) HDAC1HDAC6CXCR4CYP2D6ADORA2A
SCHEMBL4885407 0.86 HDAC1 (0.56) HDAC1HDAC6CXCR4CYP2D6ADORA2A
SCHEMBL21784360 0.85 HDAC1 (0.51) HDAC1HDAC6CXCR4CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116462711-A Bidentate nitrogen-manganese complex, preparation method thereof, catalyst composition and application 河北农业大学 2023-07-21 CN disclosed