⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904635 | 0.67 | — | — | |
| SCHEMBL9740779 | 0.67 | — | — | |
| SCHEMBL7678408 | 0.67 | — | — | |
| SCHEMBL4458774 | 0.64 | — | — | |
| SCHEMBL1526296 | 0.64 | — | — | |
| Bicarbonate SCHEMBL27895953 | 0.55 | — | — | |
| Bicarbonate SCHEMBL8388557 | 0.55 | — | — | |
| Bicarbonate SCHEMBL138927 | 0.55 | — | — | |
| SCHEMBL2953256 | 0.54 | — | — | |
| SCHEMBL871410 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785348-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013082388-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2013-06-06 | — | — | WO | disclosed |
| EP-2217226-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-08-18 | — | — | EP | disclosed |
| CN-100586485-C | Radiofluorination method of bioactive carrier | AMERSHAM HEALTH AS | 2010-02-03 | — | — | CN | disclosed |
| WO-2009061879-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
| CN-101146534-A | Substituted pyrazolopyridines, compositions containing them, method for the production thereof, and their use | AVENTIS PHARMA SA (FR) | 2008-03-19 | — | — | CN | disclosed |
| CN-1758925-A | Radiofluorination method of bioactive carrier | AMERSHAM HEALTH AS (NO) | 2006-04-12 | — | — | CN | disclosed |