⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534334 | 0.67 | — | — | |
| SCHEMBL1616586 | 0.65 | — | — | |
| SCHEMBL17673070 | 0.65 | — | — | |
| SCHEMBL17675690 | 0.65 | — | — | |
| SCHEMBL12477419 | 0.65 | — | — | |
| SCHEMBL6682603 | 0.65 | — | — | |
| SCHEMBL17675559 | 0.65 | — | — | |
| SCHEMBL6758871 | 0.65 | — | — | |
| SCHEMBL6654113 | 0.65 | — | — | |
| SCHEMBL1568344 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009453-A1 | S1P3 RECEPTOR INHIBITORS FOR TREATING INFLAMMATION | DONELLO JOHN E | 2011-01-13 | — | — | US | claimed |
| EP-2262497-A2 | S1P3 RECEPTOR INHIBITORS FOR TREATING INFLAMMATION | Allergan, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009117335-A2 | S1P3 RECEPTOR INHIBITORS FOR TREATING INFLAMMATION | ALLERGAN, INC. (US) | 2009-09-24 | — | — | WO | claimed |
| US-20070232682-A1 | Indole Compounds having sphingosine-1-phosphate (S1P) receptor antagonist | ALLERGAN, INC. (US) | 2007-10-04 | — | — | US | claimed |
| WO-2007112322-A2 | INDOLE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST AND/OR ANTAGONIST BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 2007-10-04 | — | — | WO | claimed |
| US-5210258-A | Optically active alpha-naththylalkyl ketones | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1993-05-11 | — | — | US | claimed |
| US-4952690-A | 6-substituted thia-aza compounds | CIBA-GEIGY CORPORATION (US) | 1990-08-28 | — | — | US | claimed |
| EP-0081993-B1 | OPTICALLY ACTIVE ALPHA-SUBSTITUTED ARYL KETONES, THEIR PREPARATION AND THEIR USE IN PREPARING ALPHA-ARYLALKANOIC ACIDS | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1988-08-17 | — | — | EP | claimed |
| US-4605758-A | Preparation of α-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) | 1986-08-12 | — | — | US | claimed |
| US-4579684-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | claimed |
| EP-0081993-A2 | Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-22 | — | — | EP | claimed |
| US-4301279-A | Process for the production of 3-hydroxy compounds | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | claimed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | claimed |
| JP-2262533-A | — | — | None | — | — | JP | disclosed |
| WO-2024143336-A1 | HYDRAZIDE COMPOUND AND AGRICULTURAL/HORTICULTURAL BACTERICIDAL AGENT | 日本曹達株式会社 | 2024-07-04 | — | — | WO | disclosed |
| EP-4379068-A1 | IRIDOID OR SECO-IRIDOID DERIVATIVES AND THEIR USE IN A TANNING PROCESS | Institut National Des Sciences Appliquées De Rouen (FR) | 2024-06-05 | — | — | EP | disclosed |
| EP-0016725-A1 | Process for the preparation of 3-hydroxycepham compounds | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | disclosed |
| EP-0003960-A1 | 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | disclosed |
| US-4091207-A | Prostaglandin intermediate including oxathio heterocyclic ring | PFIZER INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4070477-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |