Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.53 |
| ▸ | PPARA | Q07869 | 14/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906613 | 0.97 | PPARD (0.51) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2900832 | 0.96 | PPARD (0.51) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2906223 | 0.89 | PPARD (0.55) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2906323 | 0.89 | PPARD (0.55) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2903628 | 0.88 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL2906331 | 0.88 | PPARD (0.54) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2903770 | 0.88 | PPARD (0.54) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2906075 | 0.87 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL2906309 | 0.87 | PPARD (0.53) | PPARDPPARAPPARGALDH1A1L3MBTL1 | |
| SCHEMBL2900692 | 0.87 | PPARD (0.54) | PPARDPPARAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951692-B1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-08-18 | — | — | EP | claimed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | claimed |
| EP-1951692-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2008-08-06 | — | — | EP | claimed |
| WO-2007056496-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2007-05-18 | — | — | WO | claimed |
| EP-1951692-B1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-08-18 | — | — | EP | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| WO-2007056496-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | PPARD, PPARG, PPARA | PPARD 1/4885PPARA 3/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.