Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | DNM2 | P50570 | 2/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27443494 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| SCHEMBL22631540 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| SCHEMBL28318346 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| SCHEMBL28459714 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| SCHEMBL2129584 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| SCHEMBL8410933 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| SCHEMBL19894618 | 0.98 | EPHX1 (0.46) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| Hydrochloric Acid SCHEMBL28625841 | 0.96 | EPHX1 (0.44) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| Water SCHEMBL28739412 | 0.96 | EPHX1 (0.44) | EPHX1DNM1ALDH1A1TSHRADH1B | |
| Hydrochloric Acid SCHEMBL29068586 | 0.96 | EPHX1 (0.44) | EPHX1DNM1ALDH1A1TSHRADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116559150-A | Luminescent substrate enhancer, preparation method thereof and kit | 深圳市天大生物医疗器械有限公司 | 2023-08-08 | — | — | CN | disclosed |