Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853271 | 0.85 | CA1 (0.46) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL15750380 | 0.84 | CA1 (0.49) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL1369240 | 0.83 | CA1 (0.52) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL1563568 | 0.83 | CA1 (0.52) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL1371004 | 0.83 | CA1 (0.52) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL23658911 | 0.82 | CA1 (0.47) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL20254237 | 0.82 | CA1 (0.47) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL20254210 | 0.82 | CA1 (0.47) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL15780509 | 0.82 | CA1 (0.47) | CA1CA2CA7CYP2D6KMT2A | |
| SCHEMBL26533130 | 0.82 | CA1 (0.47) | CA1CA2CA7CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745292-A | Substituted pyridotriazine compounds and uses thereof | 吉利德科学公司 | 2023-09-12 | — | — | CN | disclosed |