Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 5/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30549460 | 1.00 | KDM4E (0.59) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL10176182 | 0.81 | FLT3 (0.54) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL5828060 | 0.78 | MEN1 (0.71) | KDM4ETSHRFLT3NPC1RAB9A | |
| SCHEMBL10084615 | 0.77 | KDM4E (0.62) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL13383377 | 0.76 | KDM4E (0.60) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL21013557 | 0.76 | KDM4E (0.60) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| 5-Fluoroindole-2-Carboxylic Acid SCHEMBL209759 | 0.75 | KDM4E (1.00) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| 5-Fluoroindole-2-Carboxylic Acid SCHEMBL213473 | 0.73 | KDM4E (0.96) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL31060211 | 0.73 | FLT3 (1.00) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL17327557 | 0.72 | EGFR (0.75) | KDM4EPDPK1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368289-B | Antitumor bisindolyl methane derivative compound and preparation method and application thereof | 常州大学 | 2023-08-01 | — | — | CN | disclosed |