Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27124476 | 0.86 | ENPP1 (0.49) | DYRK1AL3MBTL1ALDH1A1POLBHTT | |
| SCHEMBL26907954 | 0.80 | MAPT (0.38) | DYRK1AL3MBTL1ALDH1A1POLBHTT | |
| Hydrochloric Acid SCHEMBL27116779 | 0.72 | ENPP1 (0.52) | ALDH1A1POLBHTTENPP3ENPP1 | |
| Hydrochloric Acid SCHEMBL27116242 | 0.70 | CA1 (0.57) | ALDH1A1POLBENPP3ENPP1SMN1; SMN2 | |
| SCHEMBL29770020 | 0.69 | ENPP1 (0.47) | NR1I2L3MBTL1ALDH1A1ENPP3ENPP1 | |
| SCHEMBL27117214 | 0.69 | ENPP1 (0.47) | NR1I2L3MBTL1ALDH1A1POLBENPP3 | |
| SCHEMBL27193096 | 0.69 | ENPP1 (0.43) | L3MBTL1ENPP3ENPP1SMN1; SMN2CA12 | |
| SCHEMBL27115888 | 0.69 | ENPP1 (0.47) | NR1I2L3MBTL1ALDH1A1ENPP3ENPP1 | |
| SCHEMBL29769998 | 0.69 | ENPP1 (0.46) | NR1I2L3MBTL1ALDH1A1ENPP3ENPP1 | |
| SCHEMBL27117840 | 0.69 | ENPP1 (0.46) | NR1I2L3MBTL1ALDH1A1ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | disclosed |