SCHEMBL29070733

SCHEMBL29070733

C#Cc1cn(C2CC(O)C(CO)O2)c(=O)nc1N

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.60
ADRB1 P08588 1/20 0.60
DNMT3B Q9UBC3 2/20 0.52
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
TK1 P04183 2/20 0.48
PNP P00491 1/20 0.47
TP53 P04637 1/20 0.47
HTT P42858 1/20 0.47
PDE4D Q08499 1/20 0.47
PDE3A Q14432 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
FPR2 P25090 1/20 0.46
ALOX12 P18054 1/20 0.46
ADRA1A P35348 1/20 0.46
TK2 O00142 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15740192 1.00 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5982159 1.00 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL6906161 1.00 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL6906164 1.00 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5982164 1.00 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983326 0.89 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983324 0.89 DNMT1 (0.60) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL13293701 0.88 DNMT1 (0.45) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL10015665 0.87 DNMT1 (0.53) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL25492471 0.87 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751260-B Method for generating universal multiple color development material with controllable size through cascade polymerization reaction 苏州有诺真生物科技有限公司 2024-05-28 CN disclosed
CN-116751260-A Method for generating universal multiple color development material with controllable size through cascade polymerization reaction 苏州有诺真生物科技有限公司 2023-09-15 CN disclosed