Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | INPPL1 | O15357 | 8/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | INPP5B | P32019 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431782 | 0.94 | INPPL1 (0.46) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL30744579 | 0.94 | INPPL1 (0.46) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL28794879 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| Phosphoric Acid SCHEMBL28141289 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL27910299 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL30643908 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL6739019 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL27864987 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| SCHEMBL21541942 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B | |
| Ammonia Solution, Strong SCHEMBL27891990 | 0.92 | INPPL1 (0.44) | TRPV1INPPL1INPP5AAKT1INPP5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751421-A | Weather-resistant and oxidation-resistant modified plastic particles and preparation method thereof | 安徽海铭塑业有限公司 | 2023-09-15 | — | — | CN | disclosed |