Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | UBE2N | P61088 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 7/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947498 | 0.83 | KDM4E (0.60) | KDM4EUBE2NHTR6ALDH1A1IMPDH2 | |
| SCHEMBL1418894 | 0.83 | KDM4E (0.68) | KDM4EUBE2NHTR6ALDH1A1IMPDH2 | |
| SCHEMBL30558132 | 0.83 | KDM4E (0.60) | KDM4EUBE2NHTR6DRD3ALDH1A1 | |
| SCHEMBL14734960 | 0.83 | KDM4E (0.60) | KDM4EUBE2NHTR6DRD3ALDH1A1 | |
| SCHEMBL30558112 | 0.83 | KDM4E (0.68) | KDM4EUBE2NHTR6ALDH1A1IMPDH2 | |
| SCHEMBL30542061 | 0.80 | KDM4E (0.77) | KDM4EUBE2NHTR6ALDH1A1HTT | |
| SCHEMBL946340 | 0.80 | KDM4E (0.77) | KDM4EUBE2NHTR6ALDH1A1HTT | |
| SCHEMBL14734918 | 0.80 | KDM4E (0.56) | KDM4EUBE2NHTR6DRD3ALDH1A1 | |
| SCHEMBL723339 | 0.79 | KDM4E (0.81) | KDM4EUBE2NHTR6HTR1ADRD3 | |
| SCHEMBL29576861 | 0.79 | KDM4E (0.81) | KDM4EUBE2NHTR6HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693503-A | Quinolinone derivative containing sulfonyl substituted indolyl acylhydrazone structure on 1-position nitrogen atom, and preparation method and application thereof | 太原理工大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116693503-A | Quinolinone derivative containing sulfonyl substituted indolyl acylhydrazone structure on 1-position nitrogen atom, and preparation method and application thereof | 太原理工大学 | 2023-09-05 | — | — | CN | disclosed |