Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 18/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.43 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580724 | 1.00 | HIF1A (0.58) | HIF1ACA12CA1CA2LMNA | |
| Cyclohexane SCHEMBL2442670 | 0.95 | HIF1A (0.58) | HIF1ACA12CA1CA2LMNA | |
| SCHEMBL2448188 | 0.85 | HIF1A (0.46) | HIF1A | |
| Benzothiophene SCHEMBL2439236 | 0.83 | HIF1A (0.44) | HIF1A | |
| SCHEMBL496601 | 0.82 | HIF1A (0.65) | HIF1A | |
| SCHEMBL9046980 | 0.82 | HIF1A (0.43) | HIF1A | |
| SCHEMBL1809709 | 0.81 | HIF1A (0.58) | HIF1A | |
| SCHEMBL3434886 | 0.81 | HIF1A (0.61) | HIF1A | |
| SCHEMBL20189383 | 0.80 | HIF1A (0.67) | HIF1A | |
| SCHEMBL29581929 | 0.80 | HIF1A (0.56) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677608-B | Benzisoxazole-3-carboxamide compound and synthesis and application thereof | 复旦大学 | 2024-06-07 | — | — | CN | claimed |
| CN-117836306-A | Galactose glycoside derivatives as galectin-3 inhibitors | 株式会社蒂奥姆生物 | 2024-04-05 | — | — | CN | claimed |
| EP-3472149-B1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | Orion Ophthalmology LLC (US) | 2023-08-30 | — | — | EP | claimed |
| CN-115677608-A | Benzisoxazole-3-formamide compound and synthesis and application thereof | 复旦大学 | 2023-02-03 | — | — | CN | claimed |
| US-12281101-B2 | Bicyclic lactams and methods of use thereof | GENENTECH, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| CN-115677608-B | Benzisoxazole-3-carboxamide compound and synthesis and application thereof | 复旦大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-115677608-B | Benzisoxazole-3-carboxamide compound and synthesis and application thereof | 复旦大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-115677608-B | Benzisoxazole-3-carboxamide compound and synthesis and application thereof | 复旦大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-117836306-A | Galactose glycoside derivatives as galectin-3 inhibitors | 株式会社蒂奥姆生物 | 2024-04-05 | — | — | CN | disclosed |
| CN-115677608-A | Benzisoxazole-3-formamide compound and synthesis and application thereof | 复旦大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115677608-A | Benzisoxazole-3-formamide compound and synthesis and application thereof | 复旦大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115677608-A | Benzisoxazole-3-formamide compound and synthesis and application thereof | 复旦大学 | 2023-02-03 | — | — | CN | disclosed |
| US-5225412-A | Antipsychotic | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-06 | — | — | US | disclosed |
| US-5225412-A | Antipsychotic | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0511610-A1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-04 | — | — | EP | disclosed |
| EP-0511610-A1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-04 | — | — | EP | disclosed |
| EP-0511610-A1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-04 | — | — | EP | disclosed |
| US-5143923-A | Psychological disorders | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5143923-A | Psychological disorders | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5143923-A | Psychological disorders | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281101-B2 | Bicyclic lactams and methods of use thereof | LSS, LPXN, CYP1B1 | HIF1A 3643/4885CA12 2507/4885CA1 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.