Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK1 | P57059 | 2/20 | 0.81 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.81 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.81 |
| ▸ | SYK | P43405 | 9/20 | 0.67 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 6/20 | 0.63 |
| ▸ | HCK | P08631 | 1/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612069 | 1.00 | SIK1 (0.81) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL31612066 | 0.95 | SIK1 (0.73) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL31612120 | 0.95 | SIK1 (0.73) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL29076115 | 0.95 | SIK1 (0.73) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL29076112 | 0.95 | SIK1 (0.73) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL31612055 | 0.92 | SIK1 (0.74) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL31612109 | 0.92 | SIK1 (0.72) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL29076211 | 0.91 | SIK2 (0.69) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL31612060 | 0.91 | SIK2 (0.69) | SIK1SIK2SIK3SYKTNK2 | |
| SCHEMBL31612096 | 0.91 | SIK1 (0.68) | SIK1SIK2SIK3SYKTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514726-A | Pyrimidine derivative and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |