Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | XPO1 | O14980 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612128 | 1.00 | MAPK14 (0.50) | MAPK14RXFP1POLBRORCALDH1A1 | |
| SCHEMBL2949398 | 0.82 | RXFP1 (0.51) | RXFP1POLBRORCALDH1A1JUN | |
| SCHEMBL31612106 | 0.81 | LCK (0.53) | MAPK14RXFP1POLBRORCLCK | |
| SCHEMBL31612115 | 0.81 | LCK (0.51) | MAPK14RXFP1RORCLCK | |
| SCHEMBL29076331 | 0.81 | LCK (0.52) | MAPK14RXFP1POLBRORCJUN | |
| SCHEMBL31612068 | 0.81 | LCK (0.52) | MAPK14RXFP1POLBRORCJUN | |
| SCHEMBL22145718 | 0.81 | CHRNA7 (0.53) | RXFP1POLBRORCJUNNFKB1 | |
| SCHEMBL31612099 | 0.79 | SIK1 (0.43) | MAPK14RXFP1POLBRORCJUN | |
| SCHEMBL20558359 | 0.78 | RXFP1 (0.43) | MAPK14RXFP1POLBRORCALDH1A1 | |
| SCHEMBL20558361 | 0.78 | RXFP1 (0.46) | MAPK14RXFP1POLBRORCJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514726-A | Pyrimidine derivative and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |