Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 17/20 | 0.79 |
| ▸ | BCL2L1 | Q07817 | 17/20 | 0.79 |
| ▸ | BAD | Q92934 | 3/20 | 0.79 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.79 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.79 |
| ▸ | ASPH | Q12797 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735659 | 0.96 | BCL2 (0.73) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| SCHEMBL7791088 | 0.92 | BCL2L1 (0.85) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| SCHEMBL4735633 | 0.92 | BCL2L1 (0.80) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| SCHEMBL22295609 | 0.91 | BCL2L1 (0.76) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| SCHEMBL19244593 | 0.91 | BCL2 (0.76) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| Navitoclax SCHEMBL10316178 | 0.88 | BCL2L1 (1.00) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| Navitoclax SCHEMBL30255921 | 0.88 | BCL2L1 (1.00) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| Navitoclax SCHEMBL15005512 | 0.88 | BCL2L1 (1.00) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| Navitoclax SCHEMBL522847 | 0.88 | BCL2L1 (1.00) | BCL2BCL2L1BADBCL2L2BCL2L11 | |
| Navitoclax SCHEMBL29363785 | 0.88 | BCL2L1 (1.00) | BCL2BCL2L1BADBCL2L2BCL2L11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783205-A | Compounds for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 尼坎治疗公司 | 2023-09-19 | — | — | CN | disclosed |