Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | GRB2 | P62993 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29077872 | 1.00 | PTPN1 (0.44) | PTPN1KMT2AFURINGRB2CASP3 | |
| SCHEMBL29077936 | 1.00 | PTPN1 (0.44) | PTPN1KMT2AFURINGRB2CASP3 | |
| SCHEMBL29077921 | 1.00 | PTPN1 (0.44) | PTPN1KMT2AFURINGRB2CASP3 | |
| SCHEMBL29077866 | 1.00 | PTPN1 (0.44) | PTPN1KMT2AFURINGRB2CASP3 | |
| SCHEMBL29609021 | 0.95 | PTPN1 (0.39) | PTPN1KMT2AFURINMAP1LC3BTLR2 | |
| SCHEMBL29609010 | 0.95 | PTPN1 (0.39) | PTPN1KMT2AFURINMAP1LC3BTLR2 | |
| SCHEMBL29608650 | 0.95 | PTPN1 (0.39) | PTPN1KMT2AFURINMAP1LC3BTLR2 | |
| SCHEMBL29610184 | 0.95 | PTPN1 (0.39) | PTPN1KMT2AFURINMAP1LC3BTLR2 | |
| SCHEMBL23880545 | 0.94 | TLR2 (0.39) | PTPN1KMT2AFURINCASP3MAP1LC3B | |
| SCHEMBL31035902 | 0.94 | TLR2 (0.39) | PTPN1KMT2AFURINCASP3MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085100-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116390771-A | Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof | 瑞泽恩制药公司 | 2023-07-04 | — | — | CN | disclosed |