Sugi Predict

Sugi Predict / Compounds / SCHEMBL29077934

SCHEMBL29077934

SCHEMBL29077934

[N-]=[N+]=NCCOCCNC(=O)CCOCC(COCCC(=O)NCCOCCN=[N+]=[N-])(COCCC(=O)NCCOCCN=[N+]=[N-])NC(=O)CCOCCOCCOCCOCCNC(=O)O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.34
▸ TTR P02766 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24620135 0.93 CRBN (0.34) CRBNTTR
SCHEMBL19437542 0.90 CRBN (0.38) CRBNTTR
SCHEMBL16329564 0.89 CRBN (0.33) CRBN
SCHEMBL24297232 0.89 CRBN (0.33) CRBN
SCHEMBL31103722 0.87 GLP1R (0.34) CRBNTTR
SCHEMBL19437456 0.86 CRBN (0.34) CRBNTTR
SCHEMBL25360279 0.86 CRBN (0.34) CRBNTTR
SCHEMBL19437525 0.86 CRBN (0.34) CRBNTTR
SCHEMBL25405274 0.86 MEN1 (0.36) TTR
SCHEMBL24297334 0.85 PLK1 (0.34) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118085100-A Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof 瑞泽恩制药公司 2024-05-28 — — CN disclosed
CN-116390771-A Camptothecin analogues conjugated to glutamine residues in proteins and uses thereof 瑞泽恩制药公司 2023-07-04 — — CN disclosed