SCHEMBL29078201

SCHEMBL29078201

Cn1nc(Cl)c2cnccc21

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 2/20 0.39
NAMPT P43490 3/20 0.39
MAOA P21397 5/20 0.38
MAOB P27338 5/20 0.38
ACHE P22303 1/20 0.38
GAA P10253 1/20 0.36
CYP2D6 P10635 1/20 0.36
NFATC1 O95644 1/20 0.35
GSK3B P49841 1/20 0.35
DYRK1A Q13627 1/20 0.35
IMPDH2 P12268 1/20 0.34
ELANE P08246 1/20 0.33
ATM Q13315 1/20 0.33
TOP2A P11388 1/20 0.33
GRM4 Q14833 1/20 0.32
CDC7 O00311 1/20 0.32
CDK2 P24941 1/20 0.32
RPS6KA5 O75582 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13041950 0.78 ADORA2A (0.50) KDM4CNAMPTMAOAMAOBACHE
SCHEMBL14075034 0.77 AXL (0.39) KDM4CNAMPTMAOAMAOBACHE
SCHEMBL31167938 0.77 AXL (0.39) KDM4CNAMPTMAOAMAOBACHE
Ammonia Solution, Strong SCHEMBL29096508 0.77 ADORA2A (0.48) KDM4CNAMPTMAOAMAOBACHE
SCHEMBL17045314 0.77 RPS6KA5 (0.43) NAMPTMAOAMAOBACHEGAA
SCHEMBL20674201 0.77 NAMPT (0.41) KDM4CNAMPTMAOAMAOBACHE
SCHEMBL18938887 0.77 NAMPT (0.39) KDM4CNAMPTMAOAMAOBACHE
SCHEMBL17559129 0.77 KAT2B (0.49) GAA
SCHEMBL17559133 0.77 KAT2B (0.49) GAA
SCHEMBL17866555 0.77 RET (0.38) CYP2D6NFATC1GSK3BDYRK1AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119156381-A Compounds and methods for treating cancer 上海睿跃生物科技有限公司 2024-12-17 CN disclosed
CN-116583509-A Compounds and methods for treating cancer 上海睿跃生物科技有限公司 2023-08-11 CN disclosed