Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15152857 | 0.83 | PDK2 (0.43) | PDK2HPGDS | |
| SCHEMBL17205525 | 0.74 | PDK2 (0.40) | PDK2HPGDS | |
| SCHEMBL28877850 | 0.73 | NAMPT (0.46) | PDK2HPGDS | |
| SCHEMBL25305221 | 0.70 | PDK2 (0.46) | PDK2HPGDS | |
| SCHEMBL15524703 | 0.69 | NAMPT (0.38) | PDK2HPGDS | |
| SCHEMBL29079125 | 0.69 | PDK2 (0.44) | PDK2ABHD6 | |
| SCHEMBL19505289 | 0.67 | PDK2 (0.41) | PDK2ABHD6HPGDS | |
| SCHEMBL827176 | 0.67 | DPP4 (0.38) | — | |
| SCHEMBL26074494 | 0.66 | PDK2 (0.40) | PDK2 | |
| SCHEMBL20364272 | 0.66 | PDK2 (0.40) | PDK2ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640156-A | RIPK1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-08-25 | — | — | CN | disclosed |