Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 19/20 | 0.41 |
| ▸ | JAK1 | P23458 | 19/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079610 | 0.92 | JAK2 (0.41) | JAK2JAK1IRAK4 | |
| SCHEMBL29079595 | 0.92 | JAK2 (0.48) | JAK2JAK1IRAK4 | |
| SCHEMBL29079627 | 0.91 | JAK2 (0.42) | JAK2JAK1IRAK4 | |
| SCHEMBL29079634 | 0.84 | JAK2 (0.37) | JAK2JAK1IRAK4 | |
| SCHEMBL25162926 | 0.74 | JAK2 (0.46) | JAK2JAK1IRAK4 | |
| SCHEMBL29079557 | 0.74 | KCNQ3 (0.34) | — | |
| SCHEMBL25162694 | 0.72 | JAK2 (0.45) | JAK2JAK1 | |
| SCHEMBL31211966 | 0.70 | JAK2 (0.39) | JAK2JAK1IRAK4 | |
| SCHEMBL30393484 | 0.69 | JAK2 (0.48) | JAK2JAK1IRAK4 | |
| SCHEMBL30392921 | 0.68 | JAK2 (0.38) | JAK2JAK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648248-A | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |