Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29768100 | 1.00 | CRBN (0.41) | CRBNDDB1TNFEPHX2CD274 | |
| SCHEMBL29768218 | 0.86 | CRBN (0.42) | CRBNDDB1TNFIKZF3 | |
| SCHEMBL30574628 | 0.85 | CRBN (0.41) | CRBNDDB1TNFIKZF3 | |
| SCHEMBL29079563 | 0.85 | EPHX2 (0.46) | CRBNDDB1EPHX2 | |
| SCHEMBL29768138 | 0.80 | CRBN (0.40) | CRBNDDB1TNFIKZF3 | |
| SCHEMBL31134471 | 0.78 | DDB1 (0.47) | CRBNDDB1TNFIKZF3ALDH1A1 | |
| SCHEMBL29768097 | 0.78 | DDB1 (0.41) | CRBNDDB1TNFIKZF3ALDH1A1 | |
| SCHEMBL29079636 | 0.78 | DDB1 (0.41) | CRBNDDB1TNFIKZF3ALDH1A1 | |
| SCHEMBL29768089 | 0.77 | DDB1 (0.42) | CRBNDDB1TNFIKZF3ALDH1A1 | |
| SCHEMBL29079658 | 0.77 | DDB1 (0.42) | CRBNDDB1TNFIKZF3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648248-A | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2023-08-25 | — | — | CN | disclosed |