Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.58 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30574469 | 1.00 | PDGFRB (0.60) | PDGFRBPDGFRAIDO1EP300KAT8 | |
| SCHEMBL7481439 | 0.86 | SRC (0.60) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL29079695 | 0.86 | KDR (0.60) | PDGFRBPDGFRAIDO1FGFR2SRC | |
| SCHEMBL7485861 | 0.86 | EGFR (0.66) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL4482829 | 0.84 | PDGFRB (0.60) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL7487419 | 0.83 | PDGFRB (0.70) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL14966816 | 0.83 | PDGFRB (0.59) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL3795538 | 0.82 | PDGFRB (0.65) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL4480466 | 0.82 | PDGFRB (0.61) | PDGFRBPDGFRAFGFR2SRCTGFBR1 | |
| SCHEMBL3894212 | 0.81 | SRC (0.66) | PDGFRBPDGFRAFGFR2SRCTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751162-A | Quinoline compound, preparation method thereof, pharmaceutical composition and medical application | 中国人民解放军军事科学院军事医学研究院 | 2023-09-15 | — | — | CN | disclosed |