Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30561530 | 1.00 | KDM4E (0.50) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL22527601 | 0.92 | TDP1 (0.56) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL30541933 | 0.92 | TDP1 (0.56) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL25366880 | 0.90 | CYP1A2 (0.42) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL30528601 | 0.90 | CYP1A2 (0.42) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL30561518 | 0.83 | NR1H2 (0.39) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL20704242 | 0.83 | NR1H2 (0.39) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL6729175 | 0.83 | NR1H2 (0.44) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL30561513 | 0.83 | NR1H2 (0.44) | KDM4EMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7800083 | 0.82 | HRH3 (0.41) | KDM4EMEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094253-B | 1, 2-dihydro-3H-pyrazolo [3,4-d ] pyrimidin-3-one analogs | 里科瑞尔姆IP控股有限责任公司 | 2023-08-29 | — | — | CN | disclosed |