Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30551259 | 0.85 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL25322160 | 0.85 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL29477676 | 0.85 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL24365179 | 0.85 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL29477605 | 0.83 | PIK3CD (0.41) | NAMPTPIK3CDABL1ACACBIDO1 | |
| SCHEMBL24365687 | 0.83 | PIK3CD (0.41) | NAMPTPIK3CDABL1ACACBIDO1 | |
| SCHEMBL25323411 | 0.81 | PIK3CD (0.36) | PIK3CDPIK3CA | |
| SCHEMBL25323407 | 0.81 | PIK3CD (0.36) | PIK3CDPIK3CA | |
| SCHEMBL30551038 | 0.81 | PIK3CD (0.36) | PIK3CDPIK3CA | |
| SCHEMBL24365203 | 0.81 | ELANE (0.34) | PIK3CDABL1PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4188920-A1 | PIPERIDIN-1-YL-N-PYRYDINE-3-YL-2-OXOACETAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MTA-ACCUMULATING CANCERS | Tango Therapeutics, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |