Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29081246 | 1.00 | TLR8 (0.37) | TLR8CHEK2GPR119HCAR1MELK | |
| SCHEMBL29081922 | 1.00 | TLR8 (0.37) | TLR8CHEK2GPR119HCAR1MELK | |
| SCHEMBL25912068 | 0.96 | TLR8 (0.38) | TLR8CHEK2GPR119MELKPIK3CD | |
| SCHEMBL29081533 | 0.96 | TLR8 (0.38) | TLR8CHEK2GPR119MELKPIK3CD | |
| SCHEMBL29081534 | 0.96 | TLR8 (0.38) | TLR8CHEK2GPR119MELKPIK3CD | |
| SCHEMBL25912011 | 0.96 | TLR8 (0.38) | TLR8CHEK2GPR119MELKPIK3CD | |
| SCHEMBL29081867 | 0.92 | TLR8 (0.38) | TLR8GPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29081866 | 0.92 | TLR8 (0.38) | TLR8GPR119PIK3CDPIK3CAPIK3CB | |
| SCHEMBL25911939 | 0.92 | TLR8 (0.40) | TLR8CHEK2GPR119PIK3CDPIK3CA | |
| SCHEMBL25430306 | 0.89 | IRAK4 (0.34) | TLR8CHEK2GPR119PIK3CDSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |