Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SGK1 | O00141 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26980229 | 0.92 | SMN1; SMN2 (0.45) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL30559619 | 0.91 | NR4A2 (0.43) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL26980760 | 0.91 | NR4A2 (0.43) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL26980246 | 0.90 | CCR4 (0.43) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL29903833 | 0.90 | CCR4 (0.43) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL26980288 | 0.89 | NR4A2 (0.41) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL29903583 | 0.89 | NR4A2 (0.41) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL30559627 | 0.88 | NR4A2 (0.40) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL26980285 | 0.88 | NR4A2 (0.40) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 | |
| SCHEMBL26980766 | 0.88 | NR4A2 (0.40) | NR4A2CCR4SMN1; SMN2HIF1ASGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |