Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.86 |
| ▸ | TSHR | P16473 | 5/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL9464233 | 1.00 | — | — | |
| Alcohol SCHEMBL21416292 | 0.94 | — | — | |
| Alcohol SCHEMBL9872612 | 0.94 | — | — | |
| Alcohol SCHEMBL16612347 | 0.94 | — | — | |
| Alcohol SCHEMBL8568674 | 0.94 | — | — | |
| Alcohol SCHEMBL28096665 | 0.94 | — | — | |
| Alcohol SCHEMBL28306337 | 0.94 | — | — | |
| Alcohol SCHEMBL17770701 | 0.93 | — | — | |
| Alcohol SCHEMBL9461084 | 0.93 | TSHR (1.00) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 | |
| Alcohol SCHEMBL6910520 | 0.93 | TSHR (1.00) | ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471939-B1 | DELIVERY OF NEUTRON CAPTURE ELEMENTS FOR NEUTRON CAPTURE THERAPY | PSIMEI PHARMACEUTICALS PLC (GB) | 2010-08-18 | — | — | EP | disclosed |
| US-20100075193-A1 | Proton Conductive Membrane and Method for Producing it | RIKEN (JP) | 2010-03-25 | — | — | US | disclosed |
| US-7592039-B2 | Method for producing nanotube material and nanotube material | RIKEN (JP) | 2009-09-22 | — | — | US | disclosed |
| EP-1909295-A1 | PROTON CONDUCTIVE MEMBRANE AND PROCESS FOR PRODUCING THE SAME | Riken (JP) | 2008-04-09 | — | — | EP | disclosed |
| US-20080038492-A1 | Method for Producing Nanotube Material and Nanotube Material | RIKEN (JP) | 2008-02-14 | — | — | US | disclosed |
| US-20050180917-A1 | Delivery of neutron capture elements for neutron capture therapy | PSIMEI PHARMACEUTICALS PLC (GB) | 2005-08-18 | — | — | US | disclosed |
| EP-1471939-A1 | DELIVERY OF NEUTRON CAPTURE ELEMENTS FOR NEUTRON CAPTURE THERAPY | Psimei Pharmaceuticals Plc (GB) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003055520-A1 | DELIVERY OF NEUTRON CAPTURE ELEMENTS FOR NEUTRON CAPTURE THERAPY | PSIMEI PHARMACEUTICALS PLC (GB) | 2003-07-10 | — | — | WO | disclosed |