Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 9/20 | 0.46 |
| ▸ | CDK7 | P50613 | 7/20 | 0.45 |
| ▸ | CCNH | P51946 | 7/20 | 0.45 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.45 |
| ▸ | CCNK | O75909 | 7/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.44 |
| ▸ | CDK2 | P24941 | 7/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.44 |
| ▸ | CDK9 | P50750 | 4/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083562 | 1.00 | MAPK3 (0.46) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL24583253 | 0.91 | CDK7 (0.43) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL21178557 | 0.88 | CDK7 (0.44) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL21178547 | 0.86 | CDK7 (0.49) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL21178697 | 0.86 | CDK7 (0.42) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL21178751 | 0.85 | CDK7 (0.46) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL25420523 | 0.85 | CDK7 (0.46) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL30865698 | 0.85 | CDK7 (0.59) | CDK7CCNHMNAT1CCNKCDK12 | |
| SCHEMBL25263432 | 0.84 | CCNK (0.49) | MAPK3CDK7CCNHMNAT1CCNK | |
| SCHEMBL21178917 | 0.83 | CCNK (0.42) | MAPK3CDK7CCNHMNAT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670123-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-08-29 | — | — | CN | disclosed |