Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 19/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 18/20 | 0.52 |
| ▸ | CDK2 | P24941 | 15/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.52 |
| ▸ | CDK7 | P50613 | 9/20 | 0.52 |
| ▸ | CCNH | P51946 | 9/20 | 0.52 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.51 |
| ▸ | CDK9 | P50750 | 13/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27203215 | 1.00 | CCNK (0.52) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL24583169 | 0.90 | CCNK (0.49) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL29083556 | 0.86 | CCNK (0.55) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL29083558 | 0.86 | CCNK (0.55) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL21178818 | 0.84 | CCNK (0.57) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL21178308 | 0.83 | CCNK (0.71) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL21178637 | 0.83 | CCNK (0.56) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL21178869 | 0.83 | CCNK (0.56) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL21178630 | 0.82 | CCNK (0.53) | CCNKCDK12CDK2CCNE1CDK7 | |
| SCHEMBL24583196 | 0.82 | CCNK (0.70) | CCNKCDK12CDK2CCNE1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670123-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-08-29 | — | — | CN | disclosed |