Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 19/20 | 0.61 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 15/20 | 0.61 |
| ▸ | CDK2 | P24941 | 15/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.61 |
| ▸ | CDK9 | P50750 | 14/20 | 0.61 |
| ▸ | CDK7 | P50613 | 13/20 | 0.61 |
| ▸ | CCNH | P51946 | 13/20 | 0.61 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24583188 | 1.00 | CCNK (0.61) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24584008 | 0.93 | CCNK (0.59) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24583172 | 0.89 | CCNK (0.65) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24583171 | 0.89 | CCNK (0.65) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL26628944 | 0.88 | CCNK (0.51) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24584388 | 0.88 | CCNK (0.51) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24588975 | 0.87 | CCNK (0.63) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24583133 | 0.87 | CCNK (0.63) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL24583148 | 0.87 | CCNK (0.63) | CCNKCDK12CCNE1CDK2CCNT1 | |
| SCHEMBL26628935 | 0.87 | CCNK (0.47) | CCNKCDK12CCNE1CDK2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670123-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-08-29 | — | — | CN | disclosed |