Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084085 | 0.94 | EGFR (0.61) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL29083955 | 0.90 | EGFR (0.63) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL29084065 | 0.87 | EGFR (0.53) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL29084133 | 0.84 | EGFR (0.55) | EGFRALKINSRIGF1RJAK3 | |
| SCHEMBL29083950 | 0.84 | EGFR (0.59) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL29084163 | 0.81 | EGFR (0.62) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL29974885 | 0.80 | EGFR (0.69) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL29084167 | 0.79 | EGFR (0.70) | EGFRALKINSRIGF1RPTK2 | |
| SCHEMBL22858431 | 0.79 | EGFR (0.58) | EGFRALKINSRIGF1R | |
| SCHEMBL29508916 | 0.79 | EGFR (0.58) | EGFRALKINSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | claimed |
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022206797-A1 | EGFR INHIBITOR, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2022-10-06 | — | — | WO | disclosed |