Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599812 | 0.89 | KDM4E (0.70) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL29084455 | 0.83 | KDM4E (0.57) | GALR3KDM4ERAB9ASMN1; SMN2LMNA | |
| SCHEMBL959364 | 0.77 | KDM4E (1.00) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL29709972 | 0.77 | KDM4E (1.00) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7351475 | 0.77 | NPC1 (0.73) | GALR3KDM4ERAB9ASMN1; SMN2LMNA | |
| SCHEMBL29687771 | 0.76 | KDM4E (0.71) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL7349354 | 0.76 | KDM4E (0.71) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL4603661 | 0.76 | KDM4E (0.60) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL928139 | 0.74 | KDM4E (0.72) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL958967 | 0.74 | KDM4E (0.72) | KDM4ERAB9ASMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438162-A | Modulators of MAS-related G protein receptor X4 and related products and methods | 伊赛恩特制药公司 | 2023-07-14 | — | — | CN | disclosed |