Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | TRPC6 | Q9Y210 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29085224 | 0.86 | GPR6 (0.46) | GPR6HPGDSTRPC6RAB9APDCD1 | |
| SCHEMBL29085228 | 0.86 | GPR6 (0.46) | GPR6HPGDSTRPC6RAB9APDCD1 | |
| SCHEMBL29085222 | 0.83 | PARP1 (0.49) | RAB9APARP1 | |
| SCHEMBL29085248 | 0.81 | GPR6 (0.44) | GPR6HPGDSTRPC6PDCD1CD274 | |
| SCHEMBL29085166 | 0.80 | SCN9A (0.37) | HPGDSRAB9APARP1KARS1 | |
| SCHEMBL29085247 | 0.79 | CNR2 (0.37) | HPGDSRAB9APARP1 | |
| SCHEMBL29085194 | 0.79 | GPR6 (0.47) | GPR6HPGDSTRPC6RAB9APDCD1 | |
| SCHEMBL30064550 | 0.79 | GPR6 (0.47) | GPR6HPGDSTRPC6RAB9APDCD1 | |
| SCHEMBL29085197 | 0.79 | GPR6 (0.47) | GPR6HPGDSTRPC6RAB9APDCD1 | |
| SCHEMBL29085171 | 0.77 | USP30 (0.48) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867783-A | Pyridine derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2022222964-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-10-27 | — | — | WO | disclosed |