Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | GRK5 | P34947 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617643 | 1.00 | S1PR5 (0.45) | S1PR5S1PR1GRK5CDK8PAX8 | |
| SCHEMBL30646801 | 1.00 | S1PR5 (0.45) | S1PR5S1PR1GRK5CDK8PAX8 | |
| SCHEMBL29087685 | 1.00 | S1PR5 (0.45) | S1PR5S1PR1GRK5CDK8PAX8 | |
| SCHEMBL29617602 | 0.92 | S1PR5 (0.52) | S1PR5S1PR1GRK5CDK8PDGFRA | |
| SCHEMBL29617613 | 0.87 | PSEN1 (0.48) | S1PR5S1PR1GRK5CDK8HIF1A | |
| SCHEMBL30646794 | 0.87 | PSEN1 (0.48) | S1PR5S1PR1GRK5CDK8HIF1A | |
| SCHEMBL29087732 | 0.87 | PSEN1 (0.48) | S1PR5S1PR1GRK5CDK8HIF1A | |
| SCHEMBL29617639 | 0.87 | CHRM2 (0.46) | S1PR5S1PR1GRK5CDK8HIF1A | |
| SCHEMBL29087738 | 0.87 | CHRM2 (0.46) | S1PR5S1PR1GRK5CDK8HIF1A | |
| SCHEMBL29087736 | 0.87 | CHRM2 (0.46) | S1PR5S1PR1GRK5CDK8HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |