Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.59 |
| ▸ | JAK2 | O60674 | 17/20 | 0.59 |
| ▸ | JAK1 | P23458 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512191 | 0.99 | NTRK1 (0.60) | NTRK1JAK2JAK1 | |
| SCHEMBL30823617 | 0.84 | NTRK1 (0.71) | NTRK1JAK2JAK1 | |
| SCHEMBL21510310 | 0.84 | NTRK1 (0.71) | NTRK1JAK2JAK1 | |
| SCHEMBL21510314 | 0.83 | NTRK1 (0.62) | NTRK1JAK2JAK1 | |
| SCHEMBL21510312 | 0.83 | NTRK1 (0.62) | NTRK1JAK2JAK1 | |
| SCHEMBL23368767 | 0.81 | NTRK1 (0.60) | NTRK1JAK2JAK1 | |
| SCHEMBL23368574 | 0.81 | NTRK1 (0.57) | NTRK1JAK2 | |
| SCHEMBL23473897 | 0.80 | NTRK1 (0.62) | NTRK1JAK2 | |
| SCHEMBL23473895 | 0.78 | NTRK1 (0.64) | NTRK1JAK2 | |
| SCHEMBL19547508 | 0.78 | NTRK1 (0.71) | NTRK1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156813-B | Heterocyclic compounds as TRK inhibitors | 北京诺诚健华医药科技有限公司 | 2023-07-25 | — | — | CN | disclosed |