Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
| ▸ | GABRD | O14764 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.42 |
| ▸ | GABRE | P78334 | 3/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5984515 | 0.77 | HTT (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL680855 | 0.73 | FGFR1 (0.56) | EGFRMKNK2CYP1A2TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL4456679 | 0.72 | FGFR1 (0.54) | EGFRMKNK2CYP1A2TSHRCYP3A4 | |
| SCHEMBL26126509 | 0.70 | BCHE (0.42) | HTR3AMKNK2CYP1A2TSHRCYP3A4 | |
| SCHEMBL27754086 | 0.70 | PDE10A (0.44) | EGFRMKNK2CYP1A2TSHRCYP3A4 | |
| SCHEMBL30677290 | 0.70 | CYP1A2 (0.46) | GABRG2GABRB3GABRA5MKNK2CYP1A2 | |
| SCHEMBL4542537 | 0.70 | POLB (0.54) | MKNK2CYP1A2TSHRCYP3A4CLK4 | |
| SCHEMBL29240138 | 0.70 | PI4KA (0.57) | GABRG2GABRB3GABRA5EGFRMKNK2 | |
| SCHEMBL6944930 | 0.69 | PI4KA (0.55) | GABRG2GABRB3GABRA5MKNK2CYP1A2 | |
| SCHEMBL6942099 | 0.69 | MKNK2 (0.40) | GABRG2GABRB3GABRA5MKNK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903586-A | Bicyclic heteroaryl containing compounds | 正大天晴药业集团股份有限公司 | 2023-10-20 | — | — | CN | disclosed |