Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 3/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29841615 | 1.00 | SOS1 (0.59) | SOS1NOTUMCFTRMRGPRX4KDM4E | |
| SCHEMBL29192882 | 0.84 | SOS1 (0.48) | SOS1NOTUMKDM4EKMT2ACCR6 | |
| SCHEMBL30825403 | 0.84 | SOS1 (0.48) | SOS1NOTUMKDM4EKMT2ACCR6 | |
| SCHEMBL29841573 | 0.81 | SOS1 (0.63) | SOS1NOTUMCFTRMRGPRX4KMT2A | |
| SCHEMBL29089686 | 0.81 | SOS1 (0.63) | SOS1NOTUMCFTRMRGPRX4KMT2A | |
| SCHEMBL23065962 | 0.77 | NOTUM (0.50) | SOS1NOTUMCFTRMRGPRX4KDM4E | |
| SCHEMBL2295241 | 0.75 | SOS1 (0.58) | SOS1NOTUMCFTRMRGPRX4KDM4E | |
| SCHEMBL3410570 | 0.75 | SOS1 (0.41) | SOS1NOTUMKDM4EKMT2ACCR6 | |
| SCHEMBL30296812 | 0.75 | SOS1 (0.41) | SOS1NOTUMKDM4EKMT2ACCR6 | |
| SCHEMBL21200958 | 0.74 | NOTUM (0.50) | SOS1NOTUMCFTRNR4A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888112-A | Lactams as CBL-B inhibitors | 基因泰克公司 | 2023-10-13 | — | — | CN | disclosed |