Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057686 | 1.00 | SPPL2A (0.61) | SPPL2AKMT2AMLNRABCB11LMNA | |
| SCHEMBL1054255 | 0.93 | SPPL2A (0.61) | SPPL2AKMT2AMLNRABCB11LMNA | |
| SCHEMBL1056483 | 0.92 | SPPL2A (0.64) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1058448 | 0.86 | SPPL2A (0.69) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1058175 | 0.85 | SPPL2A (0.61) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL6449637 | 0.84 | SPPL2A (0.67) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1056779 | 0.84 | SPPL2A (0.67) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL14338808 | 0.82 | SPPL2A (0.76) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1057249 | 0.82 | SPPL2A (0.65) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1055917 | 0.81 | SPPL2A (0.73) | SPPL2AMLNRABCB11LMNACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216334-A1 | Hiv protease inhibiting sulfonamides | Abbott Laboratories (US) | 2010-08-11 | — | — | EP | disclosed |