Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126365 | 0.90 | KMT2A (0.44) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL28335815 | 0.88 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL28707225 | 0.88 | KMT2A (0.47) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL25268241 | 0.87 | KMT2A (0.46) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL29468817 | 0.87 | TLR2 (0.38) | KMT2ATLR2FABP5FABP7CASP3 | |
| SCHEMBL16011495 | 0.86 | KMT2A (0.46) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL18528956 | 0.86 | KMT2A (0.46) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL21436038 | 0.86 | KMT2A (0.43) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL2316716 | 0.86 | KMT2A (0.46) | KMT2ATLR2FABP5FABP7CA1 | |
| SCHEMBL15878722 | 0.86 | KMT2A (0.46) | KMT2ATLR2FABP5FABP7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024234320-A1 | LONG-ACTING GLUCAGON-LIKE PEPTIDE-1 DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 南京知和医药科技有限公司 | 2024-11-21 | — | — | WO | disclosed |
| CN-118085062-A | Polypeptide derivative serving as GCGR and GLP-1R dual receptor agonist and preparation method and application thereof | 南京知和医药科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-116891522-B | Long-acting glucagon-like peptide-1 derivative and preparation method and application thereof | 南京知和医药科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116891522-A | Long-acting glucagon-like peptide-1 derivative and preparation method and application thereof | 南京知和医药科技有限公司 | 2023-10-17 | — | — | CN | disclosed |