Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29090936 | 1.00 | — | — | |
| SCHEMBL4932955 | 0.97 | — | — | |
| SCHEMBL26063476 | 0.95 | CYP2D6 (0.52) | — | |
| SCHEMBL1095019 | 0.90 | — | — | |
| SCHEMBL1641311 | 0.90 | — | — | |
| SCHEMBL1189859 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL5269479 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2886006 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2886007 | 0.87 | — | — | |
| SCHEMBL21568741 | 0.76 | CYP2D6 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |