Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.54 |
| ▸ | BRD4 | O60885 | 8/20 | 0.54 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091179 | 1.00 | CRBN (0.54) | CRBNBRD4MAP1LC3B | |
| SCHEMBL30595224 | 1.00 | CRBN (0.54) | CRBNBRD4MAP1LC3B | |
| SCHEMBL30575188 | 1.00 | CRBN (0.54) | CRBNBRD4MAP1LC3B | |
| SCHEMBL30169800 | 0.99 | CRBN (0.55) | CRBNBRD4MAP1LC3B | |
| SCHEMBL22849641 | 0.97 | CRBN (0.55) | CRBNBRD4MAP1LC3B | |
| SCHEMBL20362338 | 0.92 | CRBN (0.57) | CRBNBRD4MAP1LC3B | |
| SCHEMBL28652486 | 0.91 | CRBN (0.54) | CRBNBRD4MAP1LC3B | |
| SCHEMBL26323874 | 0.91 | CRBN (0.63) | CRBNBRD4MAP1LC3B | |
| SCHEMBL26323878 | 0.91 | CRBN (0.63) | CRBNBRD4MAP1LC3B | |
| SCHEMBL26321035 | 0.91 | CRBN (0.63) | CRBNBRD4MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693505-B | Compound for targeted degradation of EGFR protein and preparation method and application thereof | 中国药科大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116693505-A | Compound for targeted degradation of EGFR protein and preparation method and application thereof | 中国药科大学 | 2023-09-05 | — | — | CN | disclosed |