Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | SLC15A1 | P46059 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26359430 | 0.90 | ALPI (0.66) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL15679078 | 0.90 | ALPI (0.66) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL1067021 | 0.86 | SLC7A5 (0.61) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL14095409 | 0.86 | ALPI (0.61) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL6368998 | 0.86 | ALPI (0.61) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL1067018 | 0.86 | SLC7A5 (0.61) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL2785098 | 0.86 | SLC7A5 (0.70) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL23542514 | 0.85 | ALPI (0.59) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL7019120 | 0.85 | SLC7A5 (0.59) | PTGS1ALPIPKMXIAPSLC7A5 | |
| SCHEMBL18274697 | 0.85 | ALPI (0.59) | PTGS1ALPIPKMXIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854707-A | Cyclized berberine derivative and preparation method and application thereof | 石家庄学院 | 2023-10-10 | — | — | CN | disclosed |