Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067327 | 1.00 | HPGD (0.56) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL29689450 | 1.00 | HPGD (0.56) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL29091673 | 1.00 | HPGD (0.56) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL29091672 | 0.85 | HPGD (0.49) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL30615121 | 0.85 | HPGD (0.49) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL29091674 | 0.85 | HPGD (0.49) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL16108227 | 0.83 | HPGD (0.56) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL29091590 | 0.83 | HPGD (0.49) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL16108226 | 0.83 | HPGD (0.56) | HPGDKMT2AMEN1CYP1A2NPSR1 | |
| SCHEMBL29091610 | 0.83 | HPGD (0.56) | HPGDKMT2AMEN1CYP1A2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925100-A | Substituted thiophenoquinolinone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114671827-A | O-benzoylsulfimide derivative and its application | 杭州百新生物医药科技有限公司 | 2022-06-28 | — | — | CN | disclosed |