Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27031090 | 1.00 | SETD7 (0.43) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL10196598 | 0.94 | SETD7 (0.46) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL6912374 | 0.94 | SETD7 (0.46) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL10196611 | 0.94 | SETD7 (0.46) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL29092021 | 0.82 | NR1H3 (0.49) | NR1H2USP2SMN1; SMN2 | |
| SCHEMBL29092059 | 0.81 | SETD7 (0.39) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL29092034 | 0.81 | PARP1 (0.42) | NR1H2SMN1; SMN2 | |
| SCHEMBL27031154 | 0.80 | TSHR (0.44) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL27034402 | 0.78 | SETD7 (0.41) | SETD7MAP4K4GPR119NR1H2HDAC1 | |
| SCHEMBL26544023 | 0.78 | SETD7 (0.41) | SETD7MAP4K4GPR119NR1H2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940571-A | Benzisoxazole derivative and use thereof | 诺华股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116802182-A | Pyrazolopyridine derivatives and uses thereof | 诺华股份有限公司 | 2023-09-22 | — | — | CN | disclosed |