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SCHEMBL29092638

SCHEMBL29092638

CC[C@H](CS(=O)(=O)c1ccc(N2CCOCC2)cc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCN(CC4=C(c5ccc(Cl)cc5)CCC(C)(C)C4)CC3)cc2)cc1S(=O)(=O)C(F)(F)F

nearest known ligand 0.80

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 16/20 0.80
▸ BCL2 P10415 17/20 0.79
▸ BAD Q92934 3/20 0.76
▸ BCL2L2 Q92843 2/20 0.76
▸ BCL2L11 O43521 1/20 0.76
▸ CYP2C9 P11712 1/20 0.76
▸ MCL1 Q07820 1/20 0.76
▸ ASPH Q12797 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28569997 0.92 BCL2L1 (0.86) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL25600935 0.88 BCL2 (0.80) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL20812412 0.88 BCL2L1 (0.87) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL16974409 0.87 BCL2L1 (0.79) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL16264305 0.87 BCL2L1 (0.78) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL19792414 0.87 BCL2L1 (0.86) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL26647951 0.87 BCL2L1 (0.86) BCL2L1BCL2BADBCL2L2BCL2L11
Navitoclax SCHEMBL10316178 0.86 BCL2L1 (1.00) BCL2L1BCL2BADBCL2L2BCL2L11
Navitoclax SCHEMBL15005512 0.86 BCL2L1 (1.00) BCL2L1BCL2BADBCL2L2BCL2L11
SCHEMBL19091933 0.86 BCL2L1 (0.86) BCL2L1BCL2BADBCL2L2BCL2L11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116916905-A Pharmaceutical composition for treating cancer 塞莱斯蒂亚生物技术股份公司 2023-10-20 — — CN disclosed
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