Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30556715 | 1.00 | MAP2K1 (0.46) | MAP2K1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL29092460 | 0.81 | PLCG1 (0.43) | MAP2K1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL30556734 | 0.81 | ABL1 (0.42) | MAP2K1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL29093339 | 0.81 | ABL1 (0.42) | MAP2K1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL30556711 | 0.80 | MAP2K1 (0.41) | MAP2K1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL29092645 | 0.80 | MAP2K1 (0.41) | MAP2K1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL111436 | 0.74 | TDP1 (0.55) | MAP2K1KDM4ETDP1L3MBTL1MEN1 | |
| SCHEMBL29574644 | 0.74 | TDP1 (0.55) | MAP2K1KDM4ETDP1L3MBTL1MEN1 | |
| SCHEMBL29092953 | 0.73 | DHODH (0.49) | KDM4ETDP1MEN1KMT2AHTT | |
| SCHEMBL29092401 | 0.71 | DHODH (0.47) | KDM4ETDP1L3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956929-B | Heterocyclic derivative, preparation method, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |